Liver Fistula in Cats


Arteriovenous Malformation of the Liver in Cats

Intrahepatic arteriovenous (AV) fistula is generally a congenital based condition, which causes abnormal passages to develop between the proper liver (hepatic) arteries and the inner liver (intrahepatic) portal veins. It can also develop through surgical injury, trauma, and abnormal tissue or bone growth (neoplasia). Although this condition is uncommon in cats, it does occur.

This severe illness can be addressed with fair results when a proper diagnosis has been settled on. Most treatment will be on an outpatient basis and will include a planned diet, dietary restrictions, and long term observation.

Symptoms and Types

Cats suffering from AV fistula may show lethargy, anorexia, vomiting, diarrhea, weight loss, excessive thirst (polydipsia), dementia, and abdominal swelling. There are several other signs of AV fistula, such as:

  • Ascites (fluid in the abdomen)
  • Congenital heart malformations
  • Hemorrhages
  • Abnormal portal vein coagulation (thrombosis)
  • Protein loss in the kidney (nephropathy)
  • Intestinal abnormality (enteropathy) hypertension
  • Liver disease, cirrhosis of liver

The central nervous system may also be affected by this condition. Symptoms can include:

  • Distemper and other infectious disorders
  • Lead poisoning, water on the brain (hydrocephalus)
  • Idiopathic epilepsy
  • Metabolic disorders
  • Brain degeneration associated with liver failure (hepatic encephalopathy)

Causes

There is no particular breed that shows a higher predisposition than another. Hepatic AV is a vascular (vessel) malformation that is genetically determined during the embryonic stage of development – also referred to as embryologic anlage. Most conditions begin to show at an early age. In some cases of AV, surgical injury, trauma, or tumor growth (neoplasia) can lead to the problem.

Diagnosis

The disorder can be tested for by conducting a complete blood count (CBC), biochemistry, and urinalysis techniques, as well as coagulation tests, abdominal (peritoneal) fluid analysis, and an evaluation of bile acids (digestive secretion from the liver). X-rays, ultrasounds, liver biopsies, and explaratory laparotomies (incision into the abdominal wall) are other exams that may help to diagnose the liver malformation.

lethargy

The condition of being drowsy, listless, or weak

inhibit

To slow something down or cause it to stop

malformation

Any growth or organ on an animal that is not normal

thrombosis

A type of medical condition in which thrombus is created within the blood vessels

urinalysis

An in-depth examination of the properties of urine; used to determine the presence or absence of illness

hypertension

High blood pressure

polydipsia

A medical condition involving excessive thirst

hepatic

Referring to the liver

blood pressure

The amount of pressure applied by the blood on the arteries.

bile

The fluid created by the liver that helps food in the stomach to be digested.

embryonic

Something having to do with an embryo or the development of an embryo

encephalopathy

A disease of the brain of any type

abdominal wall

The abdominal wall is a group of bones, muscles, and vital tissues that make up the wall around the organs in the abdomen. Inside these bones, muscles, and tissues is a cavity, and the cavity is what houses the vital organs found inside the abdomen. The abdominal wall is vital for protection of these organs.

epilepsy

A condition of frequent or recurring seizures that are not of a system origin

hydrocephalus

A condition in which fluid is found inside the brain; water on the brain

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